一个流行病学介绍人类代谢学研究
Amit D Joshi1, Ali Rahnavard2, Priyadarshini Kachroo3
1Clinical & Translational Epidemiology Unit, Massachusetts General Hospital, Boston, MA, USA.
Trends in endocrinology and metabolism: TEM
|July 19, 2023
概括
代谢流行病学使用生物样本中的代谢物测量来了解疾病. 本综述涵盖了这个不断增长的领域的机遇,挑战和创新.
科学领域:
- 流行病学 流行病学
- 代谢学 代谢学 代谢学
- 生物化学 生物化学
背景情况:
- 代谢学提供了对生物过程和疾病病因学的见解.
- 代谢物可以在各种生物样本中测量,如血,血清和尿液.
- 代谢流行病学将代谢特征与人类健康和疾病特征联系起来.
研究的目的:
- 将代谢流行病学介绍给更广泛的科学受众.
- 讨论代谢流行病学研究中固有的机遇和挑战.
- 突出新兴的创新,用于新的生物发现.
主要方法:
- 审查当前的文献和方法在代谢流行病学.
- 从有针对性和非有针对性的测试中进行代谢物识别的讨论.
- 探索质量控制,数据协调和对高维数据的统计分析.
主要成果:
- 代谢流行病学提供了一种强大的方法来研究疾病病因学.
- 挑战包括代谢物识别,数据质量,平台协调和统计分析.
- 新兴创新对于推进该领域和发现新的见解至关重要.
结论:
- 代谢流行病学是一个有前途的领域,具有显著的生物见解潜力.
- 通过创新方法应对当前的挑战是实现这一潜力的关键.
- 需要进一步的研究和合作,才能在流行病学研究中充分利用代谢数据.
更多相关视频
07:34Large Scale Non-targeted Metabolomic Profiling of Serum by Ultra Performance Liquid Chromatography-Mass Spectrometry UPLC-MS
Published on: March 14, 2013
12.8K
07:11Author Spotlight: Emerging Technologies and Advanced Tools for Decoding Metabolomics Data Analysis
Published on: November 10, 2023
2.4K
相关概念视频
Introduction to Metabolism
105
Metabolism encompasses all biochemical reactions in a living organism, facilitating both the breakdown and synthesis of biomolecules. These metabolic processes are categorized into catabolic and anabolic pathways, which operate in a coordinated manner to ensure energy balance and cellular function.Catabolic Pathways and Energy ReleaseCatabolic pathways involve the breakdown of complex macromolecules such as carbohydrates, lipids, and proteins into smaller structures like monosaccharides, fatty...
105
What is Metabolism?
114.8K
Overview
114.8K
Overview of Metabolism
31.2K
Living cells constantly carry out various chemical reactions which are necessary for their proper functioning. These reactions are interlinked to one another via multiple pathways. The collection of these chemical reactions is known as metabolism.
Plant Metabolism
Sunlight, the primary source of energy in plants, is first absorbed by the chlorophyll pigments present in their leaves. Plants then use this energy to carry out photosynthesis, where water is oxidized into oxygen and carbon dioxide...
Plant Metabolism
Sunlight, the primary source of energy in plants, is first absorbed by the chlorophyll pigments present in their leaves. Plants then use this energy to carry out photosynthesis, where water is oxidized into oxygen and carbon dioxide...
31.2K
Introduction to Epidemiology
788
Epidemiology, known as the cornerstone of public health, involves studying the distribution and determinants of health-related events in defined populations and applying these insights to control health issues. This is essential for understanding how diseases spread, identifying populations at greater risk, and implementing measures to control or prevent outbreaks. Epidemiology addresses not only infectious diseases but also non-communicable conditions like cancer and cardiovascular disease,...
788
