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Updated: Jul 23, 2025

Mapping the Structure-Function Relationships of Disordered Oncogenic Transcription Factors Using Transcriptomic Analysis
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SIX1 和 EWS/FLI1 共同调节了尤文肉瘤中的抗转移基因网络

Connor J Hughes1,2,3, Kaiah M Fields3,4, Etienne P Danis3

  • 1Medical Scientist Training Program, University of Colorado Anschutz Medical Campus, Aurora, CO, 80045, USA.

Nature communications
|July 19, 2023
PubMed
概括

这种SIX1蛋白通过与EWS/FLI1coprotein一起工作,意外地抑制了Ewing肉瘤 (ES) 的转移. 这一发现为控制ES传播和改善患者结果提供了新的见解.

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