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Updated: Jul 23, 2025

Using Scaffold Liposomes to Reconstitute Lipid-proximal Protein-protein Interactions In Vitro
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向与胺相关蛋白1中的全位,以抑制Fis1介导的线粒体功能障碍

Luis Rios1, Suman Pokhrel1, Sin-Jin Li2,3

  • 1Department of Chemical and Systems Biology, Stanford University School of Medicine, Stanford, CA, USA.

Nature communications
|July 19, 2023
PubMed
概括

研究人员确定了SC9,一种通过准Drp1-Fis1相互作用来抑制病态线粒体裂变的小分子. 这一发现为各种疾病提供了潜在的治疗策略,而不会破坏细胞的基本功能.

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