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Updated: Jul 23, 2025

Evaluation of T Follicular Helper Cells and Germinal Center Response During Influenza A Virus Infection in Mice
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Published on: June 27, 2020

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在流感感染期间,IKK2/NFkB信号传递控制了肺部 CD8+ T 细胞记忆

Curtis J Pritzl1,2, Dezzarae Luera1,2, Karin M Knudson1

  • 1Department of Molecular Microbiology and Immunology, School of Medicine, University of Missouri, Columbia, MO, USA.

Nature communications
|July 19, 2023
PubMed
概括

在记忆形成后增强核因子kappa B (NFkB) 信号传递,提高了肺 CD8+ 组织居民记忆 (TRM) 细胞的生存率. 在免疫反应收缩期间操纵NFkB信号会损害TRM分化,突出其在TRM维护中的关键作用.

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