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Updated: Jul 23, 2025

Production of Tissue Microarrays, Immunohistochemistry Staining and Digitalization Within the Human Protein Atlas

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Published on: May 31, 2012

人类生物分子图谱计划 (HuBMAP) 的进展和前景

Sanjay Jain^1,2,3, Liming Pei⁴, Jeffrey M Spraggins⁵

¹Department of Medicine, Washington University School of Medicine, St Louis, MO, USA. sanjayjain@wustl.edu.

Nature cell biology

|July 19, 2023

概括

人类生物分子地图计划 (HuBMAP) 正在以单细胞分辨率创建人体的详细空间地图. 该倡议将提供必要的工具和数据,以推进生物医学研究和对人类组织的理解.

科学领域:

人类生物学人类生物学
生物医学研究的研究.
空间奥米克斯空间奥米克斯

背景情况:

人类生物分子图谱计划 (HuBMAP) 已经完成了初始阶段,专注于本体学,协议和管道.
该计划旨在创建一个全面的人体空间地图.

研究的目的:

引入HuBMAP计划的生产阶段.
详细说明功能组织单位的参考空间地图的生成.
开发生物医学研究的绘图工具和基础设施.

主要方法:

应用先进技术进行空间绘图.
生成单细胞分辨率数据.
整合来自不同器官和人群的数据.

主要成果:

展望概述了向HuBMAP生产阶段的过渡.
专注于创建人类组织的多尺度空间地图集.
新工具和基础设施的开发正在进行中.

结论:

在HuBMAP的生产阶段将产生有价值的空间地图和资源.
这些资源将大大推动生物医学研究.
该计划强调社区传播数据和工具.

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