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通过Mendelian随机化研究,研究血清ADAM/ADAMTS水平与骨矿物质密度之间的关联

Xin Lv1, Yuhong Lin2, Zhilei Zhang1

  • 1Department of Orthopedics, Sun Yat-sen Memorial Hospital of Sun Yat-sen University, 107 Yanjiang West Road, Guangzhou, 510120, China.

BMC genomics
|July 19, 2023
PubMed
概括

较高的ADAMTS5血清水平可能会导致脚骨矿物质密度 (BMD) 的降低. 这项孟德尔随机化研究发现,其他ADAM/ADAMTS蛋白与前臂,大腿或腰椎的BMD之间没有因果关系.

关键词:
亚当斯5 亚当斯5骨矿物质密度 骨矿物质密度遗传因果关系 遗传因果关系全基因组关联数据数据.门德尔的随机化定量式脚跟超声波 脚跟超声波

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