哥伦比亚波哥大先天性甲状腺功能低下症:当前描述 (2015-2021)
Pablo Pineda-Sanabria1, Esteban Portilla-Rojas1, María Camila León-Sanabria2
1Faculty of Medicine, Pontificia Universidad Javeriana, Bogotá, Colombia.
Journal of pediatric endocrinology & metabolism : JPEM
|July 20, 2023
概括
在波哥大,先天性甲状腺功能低下症 (CH) 每1万名新生儿中有3.29例. 诊断和治疗的延迟凸显了哥伦比亚需要改进新生儿查计划的需要.
科学领域:
- 儿科 儿科 儿科
- 内分泌学 在内分泌学.
- 公共卫生 公共卫生
背景情况:
- 先天性甲状腺功能低下症 (CH) 是新生儿可预防的神经缺陷的主要原因.
- 早期发现和治疗对于最佳的神经发育结果至关重要.
- 强制性报告系统对于监测新生儿健康状况至关重要.
研究的目的:
- 确定哥伦比亚波哥大HC的流行率和流行病学特征.
- 分析CH病例的诊断和治疗启动的及时性.
- 为改善CH查和管理的公共卫生战略提供信息.
主要方法:
- 在2015-2021年期间,在波哥大对被诊断患有CH的活产儿 (ICD-10代码E030,E031) 进行了回顾性横截面研究.
- 对病例数据的分析,包括患病率,临床分类,妊娠年龄和孕妇健康因素.
- 评估与出生和通知日期相关的治疗开始时间表.
主要成果:
- 观察到每1万个活产婴儿中有3.29例的患病率.
- 大多数病例是单独的CH (92.54%),对于妊娠年龄 (16.92%) 和早产 (26.87%),显著比例很小.
- 有相当大的比例 (66.67%) 在诊断后没有接受治疗,治疗开始的平均延迟时间长.
结论:
- 波哥大CH的患病率与全国比率相似,但低于高收入国家,这表明查计划的增强潜力.
- 诊断和治疗的重大延迟强调了急需优化护理途径的迫切需要.
- 改善哥伦比亚新生儿查计划对于及时管理CH和改善婴儿健康结果至关重要.
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