植物性饮食模式与偏头痛的临床发现之间是否存在关联?
Elham Karimi1,2, Shahnaz Amani Tirani3, Elham Sadat Azimi4
1Department of Clinical Nutrition, School of Nutrition and Food Sciences, Isfahan University of Medical Sciences, Isfahan, Iran.
Frontiers in nutrition
|July 20, 2023
概括
坚持植物性饮食可能会减少偏头痛的频率和降低氧化 (NO) 水平. 较高的植物性饮食指数 (PDI) 分数与较少的头痛和减少的NO相关,这表明有有益的饮食联系.
科学领域:
- 神经学 神经学
- 营养科学 营养科学
- 生物化学 生化学
背景情况:
- 偏头痛是一种严重的神经系统疾病,影响全球数百万人.
- 饮食模式越来越被认为是影响偏头痛病理生理学的潜在可修改因素.
- 氧化 (NO) 在偏头痛中起着复杂的作用,高水平与头痛进展有关.
研究的目的:
- 调查植物性饮食模式与伊朗人口中偏头痛的临床特征之间的关联.
- 探索植物性饮食指数 (PDI) 与头痛频率,持续时间和严重程度之间的关系.
- 检查偏头痛患者坚持植物性饮食和血清氧化 (NO) 水平之间的相关性.
主要方法:
- 一项横截面研究包括262名被诊断患有偏头痛的伊朗患者 (20-50岁).
- 用168项的半定量食物频率问卷 (FFQ) 来评估饮食摄入量,以计算总体,健康 (hPDI) 和不健康 (uPDI) 植物性饮食指数.
- 头痛特征通过30天的日记记录,使用HIT-6问卷评估残疾,使用格里斯方法测量血清NO水平.
主要成果:
- 较高的植物性饮食指数 (PDI) 平均得分与头痛频率降低有显著的相关性 (p=0.005).
- 增加的PDI得分与血清氧化 (NO) 水平呈反向关联 (p=0.028).
- 较高的健康植物性饮食指数 (hPDI) 分数与血清NO水平降低相关 (p=0.003).
结论:
- 较高的植物性饮食模式的坚持,PDI和hPDI值的升高表明,与偏头痛患者的头痛频率降低有显著关联.
- 植物性饮食可能会影响偏头痛病理生理学,部分是通过调节血清氧化 (NO) 水平.
- 这些发现支持植物性饮食在管理偏头痛临床特征方面的潜在治疗作用.
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