达比加特兰诱导的食管炎,全周围有蓝色色素
Tomonori Araki1,2,3, Kohei Hayashi1, Yuki Sonoda1
1Department of Gastroenterology and Hepatology Graduate School of Biomedical Sciences, Nagasaki University Nagasaki Japan.
DEN open
|July 20, 2023
概括
在心房动患者中,达比加特兰可以引起罕见的蓝色染色性食道炎. 切换到edoxaban解决了症状和内镜检查结果,强调需要考虑这种不良影响.
科学领域:
- 胃肠病学 胃肠病学
- 心脏病学 心脏病学
- 药理学 药理学是指药理学的学科.
背景情况:
- 达比加特兰是一种常见的抗凝剂,用于预防心房动中风.
- 消化管炎是已知的,虽然罕见,达比加特兰的不良影响.
- 食道的蓝色色素是达比加特兰诱导的食道炎的罕见表现.
研究的目的:
- 报告一种罕见的,具有蓝色色素的达比加特兰诱导食道炎病例.
- 描述这种不良影响的临床表现,诊断结果和管理.
- 强调认识到这种副作用的重要性,并考虑替代抗凝剂.
主要方法:
- 一个77岁的男性患者的病例报告,胸部紧张和厌食症.
- 诊断工作包括计算机断层扫描和食道胃两透镜.
- 治疗涉及从达比加特兰转换为埃多克萨班,随后进行一个月的监测期.
主要成果:
- 食道胃管腺镜检查显示了蓝色色素,,以及食道的狭窄.
- 在转换为埃多克萨班后,随访内镜检查显示 significant 显著改善与食道变化的解决.
- 患者的胸部紧张和厌食症的症状也消失了.
结论:
- 达比加特兰可以诱导带有特征蓝色色素的食道炎,这是一个罕见但显著的不良影响.
- 及时识别并切换到像edoxaban这样的替代抗凝剂可以带来有利的结果.
- 临床医生应警服用达比加特兰的患者的食管炎,特别是那些有症状的患者.
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