在实施低出生体重婴儿养探索研究中吸取的经验教训:一个大型的,多地点的观察性研究
Sunil S Vernekar1, Sarah Somji2, Kingsly Msimuko3
1Jawaharlal Nehru Medical College, KLE Academy of Higher Education and Research (Deemed-to-be-University), Belgaum, Karnataka, India.
概括
实施适度低出生体重婴儿的最佳婴儿养存在挑战. 这项在印度,马拉维和坦桑尼亚的混合方法研究为改善全球脆弱新生儿的护理提供了教训.
科学领域:
- 全球健康 全球健康
- 儿童营养学 儿童营养学
- 实施科学 实施科学
背景情况:
- 关于幼儿和脆弱婴儿的早期和最佳养实践,全球数据有限.
- 改善中度低出生体重婴儿 (MLBW) 的养策略对于更好的健康结果至关重要.
- 需要复杂的研究研究来理解和解决婴儿养实施的挑战.
研究的目的:
- 分享从一个复杂的,混合方法的婴儿养研究中学到的实施经验.
- 了解当前养LBW婴儿的做法和护理标准.
- 评估MLBW婴儿的婴儿食干预措施的可行性和可接受性.
主要方法:
- 一个形成性的,多地点的,观察性队列研究,采用融合的并行,混合方法设计.
- 涉及印度,马拉维和坦桑尼亚的12家医院.
- 数据收集包括图表审查 (603名MLBW婴儿),设施内观察 (148名MLBW婴儿),1年的前性随访 (1114名MLBW婴儿) 和定性访谈/讨论.
主要成果:
- 在医院级指南和对MLBW婴儿的护理提供中观察到显著的变化.
- 患者病历中缺少数据的比例很高 (89%是关于第一次食的时间,56%是关于出院的体重).
- 在观察到的婴儿中,18.5%的婴儿在达到体重目标之前就出院了;尽管面临COVID-19的挑战,但90%的队列随访得到了实现.
结论:
- 招募和跟踪弱势群体需要研究人员和社区的大量努力.
- 混合方法研究为规划针对MLBW婴儿的有针对性的干预提供了全面的理解.
- 有效的全球多站点健康研究伙伴关系对于建立一个可概括的证据基础至关重要.
更多相关视频
05:04A Common Marmoset Model of Mother-Infant Intervention for Breastfeeding Disorders in the Presence of Paternal Inhibition and Maternal Neglect
Published on: September 22, 2023
480
06:19Author Spotlight: Implications of Non-Nutritive Sucking on Speech Emergence and Infant Development
Published on: April 19, 2024
805
相关概念视频
01:11Observational Studies
Observational studies are a type of analytical study where researchers observe events without any interventions. In other words, the researcher does not influence the response variable or the experiment's outcome.
There are three types of observational studies – Prospective, retrospective, and cross-sectional.
Prospective Study
Prospective studies, also known as longitudinal or cohort studies, are carried out by collecting future data from groups sharing similar characteristics. One example of...
There are three types of observational studies – Prospective, retrospective, and cross-sectional.
Prospective Study
Prospective studies, also known as longitudinal or cohort studies, are carried out by collecting future data from groups sharing similar characteristics. One example of...
01:28Development of the Oral Microbiota
The establishment of the oral microbiome begins before birth, challenging the long-held belief that the fetal oral cavity is sterile. The presence of oral microbes such as Streptococcus and Fusobacterium in amniotic fluid suggests that microbial exposure may occur in utero, potentially through translocation from the maternal oral or gastrointestinal tract. This early colonization primes the neonatal immune system and sets the stage for subsequent microbial succession. Maternal health,...