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对运动员和年轻人的QT间隔校正方法的比较:系统性审查
Shehane Mahendran1, Ishita Gupta1, Jason Davis1,2,3
1Sydney School of Public Health, The University of Sydney, Sydney, Australia.
Clinical cardiology
|July 20, 2023
概括
纠正QT间隔的Bazett公式 (QTcB) 在精英运动员中不可靠,特别是在高和低心率的情况下. 弗里德里西亚公式 (QTcF) 在这个人群中提供了更准确的QT间隔校正.
科学领域:
- 心脏病学 心脏病学
- 运动医学 运动医学
- 身体生理学 身体生理学
背景情况:
- 精英运动员进行查,以检测突然心脏病死亡风险.
- 目前的指导方针建议Bazett公式 (QTcB) 用于运动员的QT间隔校正.
- 在运动员常见的心率上,QTcB可能不准确.
研究的目的:
- 审查有关运动员和年轻人 (14-35岁) QT 间隔校正方法的文献.
- 确定最准确的方法来计算纠正的QT (QTc) 在这个人口.
主要方法:
- 对MEDLINE,EMBASE,Scopus和SportDiscus数据库进行系统审查.
- 包括的研究比较了运动员或年轻人的至少两种QT校正方法.
- 评估了偏见的质量和风险.
主要成果:
- 十项研究符合纳入标准;九项发现高心率 (>90 BPM) 和低心率 (<60 BPM) 的QTcB不可靠.
- 没有研究支持QTcB在运动员和年轻人的使用.
- 弗里德里西亚公式 (QTcF) 在典型的运动员心率中显示出更准确的校正.
结论:
- 在运动员和年轻人的QT间隔纠正中,QTcB的准确性低于QTcF等替代算法.
- 在这个群体中,QTcF可能是首选的QTc计算方法.
- 需要进行进一步的研究,以确定特定心率的替代算法准确的QTc参考值.
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