睡眠时间与临床下 Carotid 斑块负担相关
Christian Agudelo1,2, Alberto R Ramos1,2, Hannah Gardener1,3
1Department of Neurology (C.A., A.R.R., H.G., R.L.S., T.R.), University of Miami Miller School of Medicine, FL.
Stroke
|July 20, 2023
概括
较长的睡眠时间与动脉斑块和区域的增加有关,这是中风的前体. 这一发现可能解释了长时间睡眠与中风风险之间的先前关联.
科学领域:
- 心血管健康 心血管健康
- 睡眠医学 睡眠医学
- 神经学 神经学
背景情况:
- 睡眠时间是心血管健康和中风风险的关键因素.
- 在美国,中风不成比例地影响着黑人和西班牙裔人口.
- 亚临床性动脉动脉样硬化是中风的前体.
研究的目的:
- 调查长时间和短时间的睡眠时间与亚临床性大脑动脉样硬化之间的关联.
- 在种族和种族多样化的人口中检查这些协会.
主要方法:
- 来自北曼哈顿研究 (NOMAS) 的1553名社区成年人的横截面研究.
- 睡眠时间 (短,中,长) 和白天的嗜睡是自我报告的.
- 用超声波评估的动脉样硬化测量 (斑块存在,面积,内心介质厚度).
- 对众多共变量进行调整的回归模型,包括人口统计,生活方式和病史.
主要成果:
- 长时间睡眠 (≥9小时) 与心血管斑块存在的几率增加有关 (OR,1.6;95% CI,1.1-2.4).
- 长时间的睡眠也与较大的动脉斑块面积有关 (OR,1.4;95% CI,1.0-1.9).
- 短暂的睡眠 (<7小时) 和白天的嗜睡没有显著的关联与动脉样硬化.
结论:
- 长时间的睡眠时间与亚临床性动脉动脉样硬化有关.
- 这种关联可能有助于解释长时间睡眠与中风风险之间的联系.
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