肥胖儿童的脉冲波分析,有或没有代谢综合征
Cemaliye Başaran1, Gökçen Erfidan1, Özgür Özdemir-Şimşek1
1University Health Sciences Turkey, İzmir Tepecik Training and Research Hospital, Clinic of Pediatrics, Division of Nephrology, İzmir, Turkey
Journal of clinical research in pediatric endocrinology
|July 20, 2023
概括
肥胖儿童,有或没有代谢综合征,表现为血压升高和动脉硬. 除了肥胖之外,代谢综合征并没有显著恶化这些心血管风险因素,除了中心血压.
科学领域:
- 心脏病学 心脏病学
- 儿科 儿科 儿科
- 代谢健康 代谢健康
背景情况:
- 儿童肥胖是与心血管疾病相关的日益关注的问题.
- 肥胖儿童的代谢综合征 (MS) 具有额外的心血管风险.
- 脉冲波分析 (PWA) 是一种评估动脉硬性和心血管健康的非侵入性工具.
研究的目的:
- 将MS和没有MS的肥胖儿童的PWA发现与健康的非肥胖儿童进行比较.
- 为了确定MS是否会加剧肥胖儿童的心血管风险因素.
主要方法:
- 追溯分析111名儿童 (41名MS,36名没有MS的肥胖者,34名健康对照).
- 评估了人体测量,生物化学标记,24小时门诊血压监测 (ABPM),左心室质量指数 (LVMI) 和PWA.
- 在三个组中比较测量结果.
主要成果:
- 与对照组相比,肥胖儿童 (有或没有MS) 的体重,身高和BMI SDS都较高.
- 与对照组相比,这两组肥胖患者的血压负荷,心血压,脉冲压,脉冲波速度 (PWV) 和LVMI都增加了.
- 在MS组中,中央缩和腹缩血压是最高的.
结论:
- 肥胖独立地增加了儿童的心血管风险标志物,如BP,PWV和LVMI.
- 肥胖儿童的代谢综合征不会显著恶化这些参数超出肥胖,除了24小时和白天的中央血压.
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