在患有先天性上腺增生症的儿童中查焦虑和抑郁症
Marianne Jacob1, Karen Lin-Su2, Corinne Catarozoli3
1Cooperman Barnabas Medical Center, Division of Pediatric Endocrinology, New Jersey, USA
Journal of clinical research in pediatric endocrinology
|July 20, 2023
概括
与对照组相比,患有先天性上腺增生症 (CAH) 的儿童不会表现出增加的焦虑或抑郁症状. 建议定期进行心理健康评估,因为儿童和护理人员的看法不同.
科学领域:
- 儿科内分泌学 儿科内分泌学
- 儿童和青少年精神病学 儿童和青少年精神病学
- 遗传学和遗传性疾病
背景情况:
- 先天性上腺增生 (CAH) 是一种遗传性疾病,需要终身服用药物,并存在上腺危机的风险.
- 在儿童中慢性CAH的管理可能会影响心理健康,增加对精神疾病的脆弱性.
- 在儿童CAH人群中评估焦虑和抑郁症状对于综合护理至关重要.
研究的目的:
- 评估CAH诊断的儿童中焦虑和抑郁症状的患病率和严重程度.
- 将CAH儿童的心理健康结果与甲状腺功能低下症 (HT) 的对照组进行比较.
- 调查疾病控制与儿科CAH的心理健康之间的相关性.
主要方法:
- 一项涉及34名CAH儿童和26名HT儿童 (7-17岁) 和他们的护理人员的横截面队列研究.
- 使用了经过验证的仪器,包括儿童抑郁 inventory 2 (CDI-2) 和儿童焦虑相关障碍屏幕 (SCARED).
- 自我报告和护理人员代理措施是在一次诊所访问期间收集的.
主要成果:
- 在CAH和HT对照组的儿童之间,没有发现焦虑或抑郁症状的显著差异.
- 儿童报告的焦虑和抑郁症状比他们的照顾者更多,这表明他们的感知有差异.
- 在上腺控制水平和焦虑或抑郁症状的存在之间没有观察到任何关联.
结论:
- 与甲状腺功能低下症儿童相比,患有CAH的儿童不会表现出更高水平的焦虑或抑郁.
- 儿童自我报告和照顾者代理报告之间的差异凸显了个性化心理健康评估的必要性.
- 对于患有CAH的儿童来说,无论照顾者的担忧如何,都建议定期进行心理健康查.
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