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Updated: Jul 23, 2025

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对于受控蛋白质降解的刺激反应性PROTACs

Keli An1, Xuqian Deng2, Hongli Chi2

  • 1The Key Laboratory of Biomedical Information Engineering of the Ministry of Education, School of Life Science and Technology, Bioinspired Engineering and Biomechanics Center (BEBC), Xi'an Jiaotong University, Xi'an, 710049, China.

Angewandte Chemie (International ed. in English)
|July 20, 2023
PubMed
概括

敏感刺激的蛋白质溶解向化马体 (sr-PROTACs) 是使用养策略来控制蛋白质降解而开发的. 这些sr-PROTACs在响应病理线索或外部触发器时激活,使得有毒性降低的向治疗成为可能.

关键词:
药物运输 药物运输 药物运输这就是 PROTACs.个性化医疗是个性化的医疗.它们是前药物.蛋白质降解 蛋白质降解

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