评估儿童肝炎的危险因素
Anurag Pandey1, K Rajeshwari1, Deepak Kumar1
1Department of Pediatrics, Maulana Azad Medical College and Associated Lok Nayak Hospital, New Delhi, India.
African journal of paediatric surgery : AJPS
|July 20, 2023
概括
贫困的社会经济地位和营养不良是印度儿科发热性肝 (LA) 的关键危险因素. 包括吸血和排水在内的保守管理改善了LA儿童的结果.
科学领域:
- 儿科胃肠病学 儿科胃肠病学
- 肝病学 肝病学是一种肝病学.
- 传染性疾病 传染性疾病
背景情况:
- 发烧性肝 (LA) 是发展中国家,特别是印度疾病和死亡的重要原因.
- 儿科LA的危险因素,特别是没有其他疾病的儿童,尚不清楚.
- 之前的研究已经给出了关于儿童LA的原因的不确定的结果.
研究的目的:
- 为了确定与印度儿童肝脏 (LA) 相关的风险因素.
- 评估儿科LA不同管理策略的结果.
- 调查社会经济地位和免疫缺陷在儿科LA中的作用.
主要方法:
- 在印度新德里的高等教学医院进行的前性观察性研究.
- 包括52名2个月至12岁的儿童,他们有声学确认的LA.
- 管理涉及静脉注射抗生素,调查和干预措施,如针吸入或猪尾导管排水.
主要成果:
- 患者的平均年龄为6岁4个月,男性:女性比例为1.4:1. 大约50%的儿童营养不良.
- 发烧,腹痛和食欲丧失是最常见的症状. 较差的社会经济地位和贫血被确定为重要的相关风险因素.
- 选择性免疫球蛋白A (IgA) 缺乏是最常见的原发性免疫缺陷,其次是T细胞缺陷. 临床黄,高GGT和即将发生的破裂与消光时间相关.
结论:
- 导致营养不良的贫困社会经济地位是儿科LA的重要危险因素.
- 选择性IgA缺乏症是受影响儿童中观察到的最常见的免疫缺陷.
- 保守的管理,包括吸入和皮肤通道排水,导致死亡率降低和良好的康复率.
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