吸烟对在耳鼻喉手术期间用酸甘控制低血压的影响
1Anesthesiology and Intensive Care Department, Kelkit State Hospital, Gümüshane, Turkey.
Nigerian journal of clinical practice
|July 20, 2023
概括
吸烟会降低尼糖的作用.
科学领域:
- 麻醉学 麻醉学
- 心血管生理学心血管生理学
- 耳鼻喉科 耳鼻喉科 耳鼻喉科
背景情况:
- 使用亚甘油控制的低血压在耳鼻喉 (ENT) 手术中很常见.
- 吸烟是一种普遍的习惯,已知有心血管和内皮的影响.
研究的目的:
- 为了研究吸烟对尼甘氨酸诱导的控制性低血压在血栓形成过程中的有效性和安全性的影响.
主要方法:
- 80名接受形手术的患者被分为非吸烟者 (组1) 和吸烟者 (组2).
- 控制的低血压被诱导使用酸甘油输注与普罗波的全静脉麻醉一起使用.
- 记录了血液动力学参数,药物剂量,手术持续时间和手术现场血度 (弗罗姆度量表).
主要成果:
- 吸烟者 (2组) 呈现出显著更高的Fromme尺度值,表明在手术领域有更多的出血.
- 吸烟者的平均动脉压 (MAP) 较低,而心率在特定时间点较高.
- 尼甘油诱导的低血压和反射性心动减速在吸烟者中更为明显.
结论:
- 吸烟诱导的内皮功能障碍加剧了尼甘的低血压效应,并增加了鼻腔手术期间出血的风险.
- 尼古丁对血小板功能的影响,加上尼甘的促出血作用,可能会导致吸烟者失去更多的血液.
- 麻醉科医生应考虑吸烟状态,在管理尼特洛甘油用于控制的低血压在ENT程序.
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