急性胰腺炎的过程 根据巴尔塔扎尔分类的功能衰竭患者
G Kilic1, G E Kilic2, A Ozkahraman2
1Department of Internal Medicine, Van Education and Research Hospital, Division of Gastroenterology, Van, Turkey.
Nigerian journal of clinical practice
|July 20, 2023
概括
急性胰腺炎 (AP) 的严重程度,特别是在患有功能衰竭的患者中,与巴尔塔扎尔分类有关. 入院时和72小时后严重的AP显示出与功能不全的显著关联,突出显示了肌素.
科学领域:
- 胃肠病学 胃肠病学
- 腎臟病學 (nephrology) 是一種醫學專業.
- 放射学 放射学是指放射学
背景情况:
- 急性胰腺炎 (AP) 的预后预测通常涉及多个器官系统.
- 巴尔塔扎尔分类是评估AP严重性的关键工具.
- 功能衰竭是影响AP结果的关键并发症.
研究的目的:
- 评估巴尔塔扎尔分类与衰竭患者急性胰腺炎的过程之间的关系.
- 为了确定巴尔塔扎尔得分是否可以预测AP患者的功能衰竭.
- 调查AP严重程度对脏结果的影响.
主要方法:
- 对352名住院的AP患者进行了回顾性分析.
- 使用Balthazar评分 (轻度,中度,严重) 对AP严重程度的分类.
- 在入院时和72小时后使用计算机断层扫描 (CT) 发现和统计分析 (曼-惠特尼U,独立t-test,chi-square) 评估功能不足和与Balthazar分类的相关性.
主要成果:
- 在6.2%的AP患者中存在功能衰竭.
- 入院时严重的AP显著与较高的功能不全率相关 (9.1%与0.3%,P<0.001).
- 在72小时后,轻度AP显示较低的功能衰竭率 (50.0%vs73.8%,P:0.016),而重度AP则有显著更高的发病率 (31.8%vs3.9%,P<0.001).
结论:
- 巴尔塔扎尔分类是预测急性胰腺炎中脏结果的宝贵工具.
- 血清肌素水平是重要的指标,具有预测AP疾病病程的预测价值.
- 早期的重症监护和密切监测对于管理AP患者至关重要,特别是那些患有脏并发症的患者.
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