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Updated: Jul 23, 2025

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单细胞测序分析揭示了瘤微环境细胞与乳腺癌骨转移中的氧化应激之间的关系

Minmin Zhang1, Xiao Chai1, Li Wang1

  • 1Department of Breast and Thyroid Surgery, Liuzhou People’s Hospital, Liuzhou 545006, Guangxi, People’s Republic of China.

Aging
|July 20, 2023
PubMed
概括

晚期乳腺癌 (BC) 骨转移 (BM) 涉及瘤微环境的显著变化. 中介细胞干细胞和纤维细胞增加,有助于骨重塑和癌细胞生长.

关键词:
灭症 (apoptosis) 是一种死亡的过程.骨头改造 骨头改造 骨头改造乳腺癌 骨转移 骨转移氧化应激是一种氧化应激.单细胞RNA测序的一个单细胞RNA测序.

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The Tumor Microenvironment02:17

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Every normal cell or tissue is embedded in a complex local environment called stroma, consisting of different cell types, a basal membrane, and blood vessels. As normal cells mutate and develop into cancer cells, their local environment also changes to allow cancer progression. The tumor microenvironment (TME) consists of a complex cellular matrix of stromal cells and the developing tumor. The cross-talk between cancer cells and surrounding stromal cells is critical to disrupt normal tissue...
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