预后营养指数是晚发性性结肠炎患者手术后并发症的预测标志物
Hirochika Kato1, Ryo Seishima2, Kimihiko Nakamura1
1Department of Surgery, School of Medicine, Keio University, 35 Shinanomachi , Shinjuku-ku, Tokyo, 160-8582, Japan.
World journal of surgery
|July 20, 2023
概括
晚期发作的性结肠炎 (UC) 增加了手术并发症的风险. 预后营养指数 (PNI) 可以帮助预测老年UC患者的这些风险,与其他营养标志物不同.
科学领域:
- 胃肠病学 胃肠病学
- 手术瘤学手术瘤学
- 老年医学 老年医学
背景情况:
- 需要手术的晚发性性结肠炎 (UC) 病例正在增加.
- 老年患者面临更高的术后并发症风险,需要进行彻底的手术前评估.
- 了解晚期UC手术结果的预测因素至关重要.
研究的目的:
- 评估手术前营养标志物在预测晚期UC患者手术后并发症方面的有效性.
- 为了比较晚期和早期UC之间的营养标记的预测性能.
- 确定特定的营养指数有价值的风险分层在老年UC手术患者.
主要方法:
- 对140名医疗耐药性UC患者进行手术的回顾性分析.
- 分数多项式建模以探索UC发病年龄和并发症风险之间的关联.
- 单变量和多变量逻辑回归以确定重要的营养标记.
主要成果:
- 50岁后UC发病 (晚期UC发病) 与手术部位感染和腹内的风险增加相关.
- 与早期相比,晚发UC组的并发症与较少的营养标志物显著相关.
- 预后营养指数 (PNI),来自白蛋白和淋巴细胞数量,是晚期UC中唯一显著的预测因子.
结论:
- 使用营养状况来预测晚期UC的术后并发症是具有挑战性的.
- 预后营养指数 (PNI) 显示,它有可能成为晚期和早期UC患者的有价值的营养标志物.
- PNI可能有助于对接受手术的老年UC患者进行手术前风险评估.
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