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Updated: Jul 22, 2025

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PKCα 异型抑制胰岛素信号,并加剧神经元胰岛素抵抗

Devanshi Mishra1, Ishitha Reddy1, Chinmoy Sankar Dey2

  • 1Kusuma School of Biological Sciences, Indian Institute of Technology-Delhi, New Delhi, Hauz Khas, -110016, India.

Molecular neurobiology
|July 20, 2023
PubMed
概括

蛋白激酶Cααα (PKCα) 的过度表达会破坏神经元中的胰岛素信号传递. 抑制PKCα可以增强胰岛素敏感性和葡萄糖吸收,为代谢和神经退行性疾病提供新的治疗点.

关键词:
阿尔茨海默氏症是阿尔茨海默氏症的一种疾病.胰岛素耐药性 胰岛素耐药性是一种胰岛素的信号传递.神经元神经元是一个神经元.这是一种PKCα.

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