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Updated: Jul 22, 2025

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需要RTEL1进行静音和表观基因组稳定

Margaux Olivier1, Amy Hesketh1, Marie-Noëlle Pouch-Pélissier1

  • 1Institute of Genetics Reproduction and Development (iGReD), Université Clermont Auvergne, CNRS, Inserm, F-63000 Clermont-Ferrand, France.

Nucleic acids research
|July 20, 2023
PubMed
概括

端粒延长1的DNA螺旋酶调节器 (RTEL1) 对于保持转录沉默至关重要. 失去RTEL1会破坏表观遗传标记,影响基因表达和异色染色体稳定性.

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