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在患有后传染性莱姆关节炎的患者中,对突细胞外基因组蛋白的自身免疫

Korawit Kanjana1, Klemen Strle1, Robert B Lochhead1

  • 1Center for Immunology and Inflammatory Diseases, Division of Rheumatology, Allergy, and Immunology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA.

The Journal of clinical investigation
|July 20, 2023
PubMed
概括

莱姆关节炎 (LA) 感染诱导的自身免疫性涉及T细胞向细胞外基质 (ECM) 蛋白质,特别是在具有特定HLA-DR等位基因的患者中. 这表明表位细胞扩散,而不是分子模仿,驱动LA的自身免疫反应.

关键词:
适应性免疫是一种适应性免疫.这是一种自身免疫力.细胞外矩阵是细胞外矩阵.传染性疾病传染性疾病.在T细胞,T细胞.

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