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Updated: Jul 22, 2025

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由8-oxo-7,8-dihydroguanine诱导的远程作用突变取决于APOBEC3的作用

Ruriko Fukushima1, Tetsuya Suzuki1, Akari Kobayakawa1

  • 1Graduate School of Biomedical and Health Sciences, Hiroshima University, 1-2-3 Kasumi, Minami-ku, Hiroshima 734-8553, Japan.

Mutagenesis
|July 20, 2023
PubMed
概括

氧化性DNA损伤,特别是8-oxoguanine (GO),导致突变. 这项研究发现,APOBEC3B显著减少了远离损伤部位发生的GO诱导突变.

关键词:
8 - 氧瓜氨酸是什么这是一种8-oxo-7,8-dihydroguanine.在 APOBEC3 中,APOBEC3 是远程作用的突变变异.细胞因子脱氨酶酶的作用

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