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Updated: Jul 22, 2025

Facile and Efficient Preparation of Tri-component Fluorescent Glycopolymers via RAFT-controlled Polymerization
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基于ROMP的高亲和度的甘油聚合物对曼诺斯结合性莱克具有很高的亲和度

Clément Gonnot1, Mathieu Scalabrini2, Benoit Roubinet3

  • 1Institut des Molécules et Matériaux du Mans (IMMM), UMR 6283 CNRS - Le Mans Université, Avenue Olivier Messiaen, 72085 Le Mans Cedex 9 France.

Biomacromolecules
|July 20, 2023
PubMed
概括

新型甘油聚合物是使用环开放转化聚合和后聚合修饰合成的. 这些先进的材料表现出强大的多价值抑制碳水化合物-乳氨酸相互作用,显示治疗应用的希望.

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Oligosaccharide Assembly

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Protein Glycosylation

Glycosylation, the most common post-translational modification for proteins, serves diverse functions. Adding sugars to proteins makes the proteins more resistant to proteolytic digestion. Glycosylated proteins can act as markers and receptors to promote cell-cell adhesion. Additionally, they have many essential quality control functions in the cell, such as correct protein folding and facilitating transport of misfolded proteins to the cytosol, which can be degraded.
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