Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

Heart Failure I: Introduction01:27

Heart Failure I: Introduction

20
Heart failure refers to a clinical syndrome caused by structural or functional cardiac disorders that prevent the heart from pumping an adequate amount of blood to meet the body's metabolic needs. This condition often arises from myocardial infarction or ischemia, leading to decreased cardiac output, reduced tissue perfusion, impaired gas exchange, fluid volume imbalance, and decreased functional ability.Heart failure can result from disruptions in the mechanisms that regulate cardiac output...
20
Imbalances in Cardiac Output01:26

Imbalances in Cardiac Output

1.4K
The heart's primary function is to pump blood throughout the body, maintaining a balance between blood sent out (cardiac output) and blood returning (venous return). If this balance is disrupted, it can result in congestive heart failure (CHF), a severe condition where the heart becomes an inefficient pump, leading to inadequate blood circulation.
CHF can occur due to the failure of either side of the heart. Left-side failure leads to pulmonary congestion—the right side continues to send...
1.4K
Heart Failure III: Clinical Manifestations01:26

Heart Failure III: Clinical Manifestations

24
Heart failure (HF) manifests primarily as dyspnea, fatigue, and fluid retention, resulting in peripheral and pulmonary edema. Symptoms may vary depending on which ventricle is more affected, left or right.Left-Sided Heart FailureAlso known as left ventricular failure, this condition results from the left ventricle's inability to fill or eject sufficient blood into the systemic circulation. It leads to pulmonary congestion, which occurs when the left ventricle fails to eject blood effectively...
24
Heart Failure VII: Nursing Interventions01:30

Heart Failure VII: Nursing Interventions

98
The first step in nursing management of a patient with heart failure involves thoroughly assessing the patient's medical history.Subjective Data: Obtain the patient's medical history of coronary artery disease, hypertension, myocardial infarction, and symptoms like dyspnea, orthopnea, and paroxysmal nocturnal dyspnea.Objective Data: Conduct a physical examination to identify findings such as jugular vein distention, pulmonary crackles, tachycardia, murmurs, peripheral edema, and vital signs,...
98
Pathophysiology of Heart Failure01:17

Pathophysiology of Heart Failure

1.6K
Heart failure (HF) is a progressive syndrome involving ventricles that leads to inadequate cardiac output. It can be classified based on location and output or ejection fraction. Ejection fraction (EF) is an essential measurement in the diagnosis and surveillance of HF. Reduced EF corresponds to systolic heart failure (HFrEF). However, HF with preserved ejection fraction (HFpEF) is becoming increasingly prevalent. Also known as diastolic HF, this form of HF is related to aging. The...
1.6K
Sleep Apnea01:21

Sleep Apnea

192
Sleep apnea is a condition where breathing stops intermittently during sleep, often leading to significant health issues. Each episode can last from 10 to 20 seconds or more and is frequently accompanied by a brief arousal from sleep. This disturbance, largely unnoticed by the individual, can lead to severe daytime fatigue. Commonly, individuals seek help after being informed by their partners about loud snoring and noticeable breathing pauses during sleep.
The condition is more prevalent among...
192

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

Control of microglial dynamics by the Arp2/3 complex and the autism- and schizophrenia-associated protein CYFIP1.

Proceedings of the National Academy of Sciences of the United States of America·2026
Same author

GLP-1 activates K<sub>ATP</sub> channels in coronary pericytes as the effector of brain-gut-heart signalling mediating cardioprotection.

Nature communications·2026
Same author

Anti-arrhythmic targeting of sympathetic stellate ganglion P2X3 receptors.

The Journal of physiology·2025
Same author

The vascular contribution to cognitive decline in ageing and dementia.

Nature reviews. Neuroscience·2025
Same author

A role for fibroblast and mural cell subsets in a nerve ligation model of neuropathic pain?

Brain, behavior, and immunity·2025
Same author

Inhibiting Ca<sup>2+</sup> channels in Alzheimer's disease model mice relaxes pericytes, improves cerebral blood flow and reduces immune cell stalling and hypoxia.

Nature neuroscience·2024

相关实验视频

Updated: Jul 22, 2025

Author Spotlight: Traditional Chinese Medicine for Sleep Disorders in Acute COPD &#8212; A Safe, Cost-Effective Approach
04:53

Author Spotlight: Traditional Chinese Medicine for Sleep Disorders in Acute COPD — A Safe, Cost-Effective Approach

Published on: October 18, 2024

823

心脏衰竭导致不眠之夜

Harvey Davis1, David Attwell1

  • 1Department of Neuroscience, Physiology and Pharmacology, University College London, London, UK.

Science (New York, N.Y.)
|July 20, 2023
PubMed
概括

心脏功能障碍导致免疫系统扰乱松果腺体的黑激素产生. 这项研究揭示了心脏健康与身体自然睡眠激素调节之间的联系.

科学领域:

  • 神经内分泌学
  • 免疫学
  • 心脏病学

背景情况:

  • 这种激素对睡眠和清醒周期的调节至关重要.
  • 心脏功能障碍可能导致全身炎症和免疫系统失调.
  • 梅拉在心血管健康中的作用和免疫系统对其的调节尚未完全理解.

研究的目的:

  • 研究心脏功能障碍对松果腺释放的影响.
  • 探索潜在的免疫介导机制,

主要方法:

  • 使用心脏功能障碍的动物模型.
  • 评估了桃腺中的免疫细胞透和炎症标志物.
  • 血清和松果组织中的量化黑激素水平.

主要成果:

  • 心脏功能障碍与桃腺显著的免疫细胞透有关.
  • 在心脏功能障碍的动物的松果腺中观察到炎症标志物升高.
  • 在存在心脏功能障碍时,松果腺和血清中的黑素水平显著降低.

结论:

  • 心脏功能障碍会引发免疫反应,从而损害松果腺的氨酸合成和释放.

更多相关视频

Quantifying Infra-slow Dynamics of Spectral Power and Heart Rate in Sleeping Mice
10:56

Quantifying Infra-slow Dynamics of Spectral Power and Heart Rate in Sleeping Mice

Published on: August 2, 2017

10.1K
Author Spotlight: Overcoming Challenges in Drosophila Sleep Measurement Using DAM System
05:59

Author Spotlight: Overcoming Challenges in Drosophila Sleep Measurement Using DAM System

Published on: October 20, 2023

2.4K

相关实验视频

Last Updated: Jul 22, 2025

Author Spotlight: Traditional Chinese Medicine for Sleep Disorders in Acute COPD &#8212; A Safe, Cost-Effective Approach
04:53

Author Spotlight: Traditional Chinese Medicine for Sleep Disorders in Acute COPD — A Safe, Cost-Effective Approach

Published on: October 18, 2024

823
Quantifying Infra-slow Dynamics of Spectral Power and Heart Rate in Sleeping Mice
10:56

Quantifying Infra-slow Dynamics of Spectral Power and Heart Rate in Sleeping Mice

Published on: August 2, 2017

10.1K
Author Spotlight: Overcoming Challenges in Drosophila Sleep Measurement Using DAM System
05:59

Author Spotlight: Overcoming Challenges in Drosophila Sleep Measurement Using DAM System

Published on: October 20, 2023

2.4K
  • 这些发现突显了心血管健康与神经内分泌功能之间的新联系.
  • 针对免疫路径可能为治疗心脏病患者的睡眠障碍提供治疗潜力.