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Updated: Jul 22, 2025

Standardized Data Acquisition for Neuromelanin-Sensitive Magnetic Resonance Imaging of the Substantia Nigra
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Standardized Data Acquisition for Neuromelanin-Sensitive Magnetic Resonance Imaging of the Substantia Nigra

Published on: September 8, 2021

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在精神分裂症中使用olanzapine的治疗参考范围:对血液度,临床效应和多巴胺受体占用率的系统审查

Katja Wesner1, Christoph Hiemke2,3, Niels Bergemann4,5,3

  • 1Department of Molecular Neuroimaging, Central Institute of Mental Health, Medical Faculty Mannheim, University of Heidelberg, Mannheim, Germany.

The Journal of clinical psychiatry
|July 20, 2023
PubMed
概括

这项研究建议将奥兰扎宾的治疗参考范围修订为20-40 ng/mL,以最佳治疗精神分裂症. 这个范围平衡了由多巴胺D2受体占用率指出的疗效与潜在的副作用.

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Methods for Studying the Mechanisms of Action of Antipsychotic Drugs in Caenorhabditis elegans

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Investigating the Effects of Antipsychotics and Schizotypy on the N400 Using Event-Related Potentials and Semantic Categorization12:00

Investigating the Effects of Antipsychotics and Schizotypy on the N400 Using Event-Related Potentials and Semantic Categorization

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Antipsychotic drugs are a crucial treatment method for acute and chronic psychoses, bipolar illness, and behavioral disorders. The selection of these drugs depends on several factors, including the state of the disease, clinical judgment, possible drug interactions, and the patient's sensitivity to adverse effects. In immediate scenarios, such as delirium and dementia, short-term treatment with low doses of high-potency typical or atypical agents can effectively manage symptom exacerbation.
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The term "psychosis" refers to a spectrum of mental disorders characterized by abnormal thoughts, perceptions, and behaviors. It can manifest as mood disorders, dementia, delirium with psychotic features, substance-induced psychosis with psychotic features, brief psychotic disorder, delusional disorder, schizoaffective disorder, and schizophrenia. Among all these disorders, schizophrenia is the most common psychotic disorder, affecting 1% of the worldwide population. Psychotic...
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