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人口药理动力学建模和随机模拟以支持小儿用皮马万塞林剂量选择

Mona Darwish1, Dragana Bugarski-Kirola2, David Jaworowicz3

  • 1Acadia Pharmaceuticals Inc., Princeton, NJ, USA.

Journal of clinical pharmacology
|July 20, 2023
PubMed
概括

皮马万塞林20毫克和34毫克的剂量在5-17岁的儿科患者中达到与成年人34毫克相似的稳定状态暴露. 这表明帕金森病精神病和其他神经精神疾病的治疗结果相似.

关键词:
计算建模计算建模选择剂量选择剂量选择儿科 儿科 儿科 儿科药物动力学 药物动力学皮马万塞林是什么意思?

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