大动脉硬度有助于更大的压力反应在静态手握炼在健康的年轻人和中年常态压力男性
Denis J Wakeham1, Rachel N Lord1, Jack S Talbot1
1Cardiff School of Sport and Health Sciences, Cardiff Metropolitan University, United Kingdom.
Autonomic neuroscience : basic & clinical
|July 20, 2023
概括
中枢动脉硬度显著影响运动血压反应,特别是在手握运动期间. 中年男性增加的硬会放大血压的增加,突出其在心血管调节中的作用.
科学领域:
- 心血管生理学心血管生理学
- 运动生理学 运动生理学
- 衰老研究研究 衰老研究
背景情况:
- 中心动脉硬度,以大动脉脉冲波速度 (aPWV) 衡量,随着年龄的增长而增加.
- 动脉硬会影响动态生理挑战期间的血压 (BP) 调节.
- 动脉硬在调节血压响应对等比手握运动 (HG) 和运动后肌肉缺血 (PEMI) 的作用尚不清楚.
研究的目的:
- 研究中枢动脉硬是否会影响健康男性对等方体握手运动 (HG) 和运动后肌肉缺血 (PEMI) 的压力反应.
- 为了比较年轻和中年男性之间的这些反应,有不同程度的动脉硬.
主要方法:
- 46名健康的非高血压男性 (23名年轻人,23名中年人) 接受了高血压到疲劳和2分钟的PEMI.
- 大动脉硬度 (aPWV) 在静止状态下使用平面化度测量来测量.
- 持续记录血压 (BP) 和肌肉交感神经活动 (MSNA).
- 在演习期间评估心脏输出量 (Q·c).
主要成果:
- 中年男性的aPWV比年轻男性高.
- 与年轻男性相比,中年男性在高血压期间的缩血压和MSNA的增加更大.
- 在休息时的aPWV与高血压期间的缩血压变化之间发现了强烈的相关性,以及与透气血压的中等相关性.
- 在年龄组之间没有观察到对PEMI反应的显著差异.
结论:
- 中枢动脉硬性在增加心脏输出和同情刺激的刺激期间调节压力反应,例如对称握手运动.
- 与年龄相关的动脉硬度增加有助于健康男性在运动期间过度的血压反应.
- 动脉硬是心血管对运动压力反应的关键决定因素.
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