开发一个具有有限元素的全脊柱模型,具有活跃的肌肉,以定量分析萨尔科佩尼亚对腰部负载的影响
Guangming Xu1, Ziyang Liang2, Tengfei Tian3
1College of Mechanical and Vehicle Engineering, Hunan University, Changsha, Hunan 410082, China; Guangzhou University of Chinese Medicine, Guangzhou, Guangdong 510405, China.
Computer methods and programs in biomedicine
|July 20, 2023
概括
软骨症是一种肌肉衰弱的疾病,通过改变L4-L5盘和L1脊椎的压力和应变,显著增加脊髓损伤风险. 这种经过验证的模型量化了这些风险,以更好地预防伤害.
科学领域:
- 生物力学 生物力学
- 脊柱工程 脊柱工程
- 肌肉骨研究 研究
背景情况:
- 肌肉骨不平衡,如肉,是脊柱损伤的关键因素.
- 量化这些不平衡对脊柱的影响存在重大挑战.
研究的目的:
- 建立有限元脊柱模型,分析肌肉骨失衡,特别是肉症对脊柱组织的影响.
- 量化研究萨尔科佩尼亚严重程度与脊髓组织压力和应变之间的关系.
主要方法:
- 开发并验证了有限元脊柱模型与神经肌肉模型相结合.
- 通过将起脊柱 (ES) 和多肌 (MF) 肌肉的生理横截面积 (PCSA) 减少到轻度 (60%),中度 (48%) 和严重 (36%) 来模拟的肉类.
- 分析了在不同严重程度的肉症下,在动态负荷期间脊柱组织的压力和应变变化.
主要成果:
- 与正常模型相比,在脊柱延伸过程中,sarcopenia模型在腰部组织中表现出更高的压力和应变.
- 负载度发生在特定的脊柱区域,严重的萨尔科佩尼亚中,L4-L5椎间盘 (128%) 和L1脊椎 (113%) 的压力显著增加.
- 在L5-S1段和从L3到S1的关节囊中观察到增加的应变,随着萨科佩尼亚严重程度的升级.
结论:
- 经过验证的脊柱合模型有效地分析了由肌肉骨失衡引起的脊柱损伤风险.
- 萨科佩尼亚对L4-L5椎间盘,L1脊椎和L3-S1关节囊造成高伤害风险,原因是显著的压力和应变差异.
相关概念视频
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