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Updated: Jul 22, 2025

Author Spotlight: Advancements in Molecular Biomarker Testing for Non-Squamous Non-Small Cell Lung Cancer
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KEAP1/NFE2L2路径签名优于KEAP1/NFE2L2突变状态,并揭示NSCLC中的替代路径激活突变

Christoph Arolt1, Margaret Dugan2, Robert Wild2

  • 1Institute of Pathology, University of Cologne, Faculty of Medicine and University Hospital Cologne, Cologne, Germany.

Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer
|July 20, 2023
PubMed
概括

一个新的K1N2得分准确地识别了非小细胞肺癌 (NSCLC) 中激活KEAP1/NFE2L2 (NRF2) 途径的瘤. 这种签名是选择患者接受向治疗的有希望的工具.

关键词:
这就是KEAP1的意义.肺癌是一种肺癌.这就是NRF2的NRF2.在NSCLCLC中,我们可以看到.文字转录学 (Transcriptomics) 是一个学科.

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