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Updated: Jul 22, 2025

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严重的先天性心脏缺陷和脑麻
Ester Garne1, Shona Goldsmith2, Ingeborg Barisic3
1Department of Pediatrics and Adolescent Medicine, Lillebaelt Hospital, University Hospital of Southern Denmark, Kolding, Denmark.
The Journal of pediatrics
|July 20, 2023
概括
患有严重先天性心脏缺陷 (sCHD) 的儿童患脑 (CP) 的患病率更高. 然而,这些儿童的脑膜炎往往比没有先天性异常的儿童温和得多.
科学领域:
- 儿科神经学 儿科神经学
- 心脏病学 心脏病学
- 发育儿科 发育儿科
背景情况:
- 大脑 (CP) 是一种重要的神经发育障碍.
- 严重先天性心脏缺陷 (sCHD) 是一种已知的不良神经发育结果的危险因素.
- 了解sCHD和CP之间的相互作用对于早期干预和管理至关重要.
研究的目的:
- 确定严重先天性心脏缺陷 (sCHD) 的儿童中脑 (CP) 的患病率.
- 描述患有sCHD的儿童中CP的结果和严重程度.
- 为了比较患有和没有sCHD的儿童的CP特征.
主要方法:
- 一项基于人口的数据链接研究,使用CP和先天性异常登记.
- 包括来自4个欧洲和2个澳大利亚地区 (1991-2009) 的数据.
- 适用于严重的慢性心脏病 (sCHD) 的EUROCAT定义.
主要成果:
- 在CP的患病率为2.9每1000个出生;在sCHD的患病率为2.1每1000个出生.
- 患有sCHD的儿童中有1.5%也患有CP (n=57).
- 与单独患有CP的儿童相比,患有CP和sCHD的儿童更频繁地出现单边性CP和智力障碍.
结论:
- 与一般人口相比,患有sCHD的儿童中,CP的比例明显高于一般人口.
- 患有sCHD的儿童的CP似乎在严重程度上比患有CP的儿童没有先天异常更轻微.
- 这凸显了儿童心脏病患者神经发育监测的重要性.
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