乳腺癌妇女2型糖尿病的查和管理建议
Laura Scott1, Lan-Linh Truong1, Robyn L Houlden2
1Department of Medicine, Queen's University, Kingston, Ontario, Canada.
Canadian journal of diabetes
|July 20, 2023
概括
患有乳腺癌的女性面临患2型糖尿病的风险明显更高,特别是在化疗或激素治疗后. 在这些患者中,早期对糖尿病进行查至关重要.
科学领域:
- 在瘤学瘤学.
- 内分泌学 在内分泌学.
- 公共卫生 公共卫生
背景情况:
- 乳腺癌诊断与患2型糖尿病的风险增加1.07至4.27倍有关.
- 这种高风险受到绝经后状态,激素治疗和辅助化疗等因素的影响.
- 糖尿病的风险增加似乎在乳腺癌诊断时开始,并持续10-15年.
研究的目的:
- 评估有关乳腺癌和2型糖尿病之间联系的现有证据.
- 考虑2型糖尿病查对乳腺癌患者的影响.
- 确定患有2型糖尿病风险较高的患者子组.
主要方法:
- 在2000年至2022年期间以英语出版的研究的叙事综述.
- 使用Embase和MEDLINE数据库进行了搜索.
- 关键词包括"糖尿病"和"乳腺癌".
主要成果:
- 乳腺癌诊断后至少在10至15年内,2型糖尿病的风险较高,在前两年风险最高.
- 用辅助化疗或激素治疗治疗的患者表现出特别高的风险.
- 如果由于与乳腺癌疗法相关的潜在贫血进行糖化血红蛋白检测,建议同时测量血红蛋白.
结论:
- 乳腺癌患者患2型糖尿病的风险大大增加.
- 需要进一步的研究,以便为这一群体制定具体的糖尿病查指南.
- 糖尿病治疗决策不应该被乳腺癌诊断过度影响.
关键词:
乳腺癌 乳腺癌 乳腺癌乳腺癌的癌症 乳腺癌糖尿病 糖尿病患者 糖尿病患者糖尿病是什么 糖尿病是什么检查检查检查检查检查检查检查检查检查检查检查检查检查检查药物治疗药物治疗药物疗法 药物疗法查检查 查检查 查检查 查检查更多相关视频
13:43Intraductal Delivery and X-ray Visualization of Ethanol-Based Ablative Solution for Prevention and Local Treatment of Breast Cancer in Mouse Models
Published on: April 1, 2022
4.6K
10:39Using Mouse Mammary Tumor Cells to Teach Core Biology Concepts: A Simple Lab Module
Published on: June 18, 2015
13.2K
相关概念视频
Diabetes Mellitus: Type 2 and Gestational
2.5K
Type 2 diabetes, characterized by insulin resistance, arises when the insulin receptors on cells lose responsiveness to insulin, diminishing the cell's capacity to take up glucose, resulting in elevated blood glucose levels. To receive a diagnosis of Type 2 diabetes, a series of blood glucose tests are necessary to assess whether the blood glucose falls within normal parameters. If the result is out of the normal range, a patient may be diagnosed as prediabetic or diabetic, depending on the...
2.5K
Diabetes: Management and Pharmacotherapy
319
The therapy for diabetes aims to alleviate hyperglycemia-related symptoms, prevent acute metabolic decompensation, and reduce chronic end-organ complications. Glycemic control is evaluated through short-term (self-monitoring, continuous glucose monitoring) and long-term (A1c, fructosamine) metrics, enabling near real-time tracking of blood glucose levels and reflecting glycemic control over specific time frames.
Insulin remains the cornerstone of treatment for most patients with type 1 and many...
Insulin remains the cornerstone of treatment for most patients with type 1 and many...
319
Diabetes: Symptoms, Diagnosis, and Complications
599
For most patients, experiencing several weeks of polyuria, polydipsia, fatigue, and significant weight loss may indicate the presence of diabetes. Furthermore, adults displaying the phenotypic appearance of type 2 diabetes (particularly those who are obese and not initially insulin-requiring), may have islet cell autoantibodies, suggesting autoimmune-mediated β cell destruction and a diagnosis of latent autoimmune diabetes of adults (LADA). The categorization of glucose homeostasis is...
599
Carbohydrate Metabolism
11.3K
Carbohydrates are polymers composed of molecules containing atoms of carbon, hydrogen and oxygen. One gram of carbohydrate can provide four kilo-calories of energy, which makes it the most efficient instant energy source.
Starch accounts for approximately 60% of the carbohydrates consumed by humans. Since amylase enzymes cannot function in the stomach's acidic environment, starch can only be digested in the mouth and small intestine. Simple sugars are found naturally in milk and fruits in...
Starch accounts for approximately 60% of the carbohydrates consumed by humans. Since amylase enzymes cannot function in the stomach's acidic environment, starch can only be digested in the mouth and small intestine. Simple sugars are found naturally in milk and fruits in...
11.3K
Psychoneuroimmunology: Diabetes and Cancer
48
Chronic stress has been linked to both the onset and progression of serious health conditions, including Type 2 diabetes and cancer. Type 2 diabetes, a widespread chronic illness, is closely associated with obesity and insulin resistance, both of which often worsen under stress. Studies indicate that men experiencing high levels of chronic stress face a 45% higher risk of developing diabetes compared to those with minimal stress. Stress triggers physiological responses that elevate blood...
48
Pathophysiology of Diabetes
1.0K
Diabetes mellitus is a chronic metabolic disorder characterized by hyperglycemia. The four categories of diabetes are type 1 diabetes, type 2 diabetes, other specific types of diabetes, and gestational diabetes.
Type 1 diabetes is characterized by autoimmune-mediated destruction of pancreatic β cells, with environmental factors potentially triggering this process in genetically susceptible individuals. Despite many not having a family history, certain genes increase susceptibility,...
Type 1 diabetes is characterized by autoimmune-mediated destruction of pancreatic β cells, with environmental factors potentially triggering this process in genetically susceptible individuals. Despite many not having a family history, certain genes increase susceptibility,...
1.0K
