在接受非心脏手术的高GH风险患者中进行术前炎症反应评估 (INSIGHT):前性非干预观察性研究的研究方案
Alexander Pichler1,2, Andrea Kurz3,2, Michael Eichlseder1,2
1Division of Anaesthesiology and Intensive Care Medicine 1, Medical University of Graz, Graz, Austria.
BMJ open
|July 20, 2023
概括
非心脏手术后的术后炎症与主要的心血管并发症有关. 这项研究调查了这种关联及其对风险患者的康复,损伤和认知衰退的影响.
科学领域:
- 心脏病学 心脏病学
- 麻醉学 麻醉学
- 关键护理医学 关键护理医学
- 腎臟病學 (nephrology) 是一種醫學專業.
- 神经学 神经学
背景情况:
- 在非心脏手术后,术后炎症很常见.
- 这种炎症与心血管并发症之间的联系尚未完全理解.
- 确定这种关联对于管理高危患者至关重要.
研究的目的:
- 评估术后炎症标志物和非心脏手术后主要心血管并发症之间的关联.
- 探索炎症和急性损伤,神经认知衰退和恢复 (在家的日子) 之间的关系.
- 评估炎症生物标志物对短期和长期不良结果的预测价值.
主要方法:
- 一项多中心研究,包括1400名接受非心脏手术的风险患者.
- 主要终点:C反应蛋白与30天内主要心血管并发症的相关性.
- 二级终点:炎症生物标志物 (IL-6,公素,素) 与心血管事件的关联,AKI,DAH30,NT-proBNP,以及30天和1年的神经认知衰退.
主要成果:
- 数据收集包括在手术前和后测量炎症生物标志物.
- 通过医疗记录审查和30天和1年后的电话调查来评估结果.
- 神经认知功能在手术前后使用蒙特利尔认知评估进行评估.
结论:
- 这项研究旨在澄清术后炎症在非心脏手术后不良结果中的作用.
- 结果将为更好的风险分层和患者管理提供临床实践的信息.
- 该研究将提供关于炎症,心血管事件和器官损伤之间的复杂相互作用的见解.
相关概念视频
Peripheral Artery Disease V: Postoperative Nursing Management
12
During the postoperative period, it is crucial to focus on maintaining circulation, identifying and managing potential complications, and planning for discharge.Nursing AssessmentVital signs monitoring: Regularly monitor vital signs, including blood pressure, heart rate, respiratory rate, and temperature, to detect early signs of complications such as bleeding and infection.Circulation assessment: Monitor pulses, perform Doppler assessments, and check capillary refill, color, temperature, and...
12
Aneurysm IV: Nursing Management
8
Vigilant monitoring for aneurysm rupture is essential for patients undergoing aortic surgery.Preoperative Nursing ManagementContinuously monitor the patient for manifestations of aneurysm rupture, such as pallor, weakness, tachycardia, hypotension, abdominal, back, groin, or periumbilical pain, changes in consciousness, and a pulsating abdominal mass. Regularly assess the patient's peripheral pulses.Instruct the patient to consume a clear liquid diet the day before surgery and administer...
8
Cardiomyopathy VII: Pre and Post Operative Nursing Management
16
Patients with hypertrophic cardiomyopathy (HCM) and left ventricular outflow tract (LVOT) obstruction who remain symptomatic despite optimal medical therapy may undergo a septal myectomy (Morrow procedure). This procedure involves excising a portion of the hypertrophied septum below the aortic valve using a heart-lung machine to improve blood flow through the LVOT. Effective preoperative and postoperative nursing management ensures successful patient outcomes, minimizes complications, and...
16
Endoscopic Procedures IV: Sigmoidoscopy and Laproscopy
119
Sigmoidoscopy and laparoscopy are distinct medical procedures that enable physicians to internally inspect different parts of the GI tract. Although they serve different purposes, each is essential for diagnosing and, in some cases, treating various medical conditions.
Sigmoidoscopy
Sigmoidoscopy is a diagnostic procedure that uses a flexible sigmoidoscope equipped with a light source and camera to examine the rectum and sigmoid colon. The procedure involves inserting the tube through the anus...
Sigmoidoscopy
Sigmoidoscopy is a diagnostic procedure that uses a flexible sigmoidoscope equipped with a light source and camera to examine the rectum and sigmoid colon. The procedure involves inserting the tube through the anus...
119
SBAR II: Application of SBAR
4.5K
SBAR is an effective communication tool used by healthcare professionals to communicate patient information accurately. SBAR stands for Situation, Background, Assessment, and Recommendation. For a better understanding, an example is given below.
SBAR Report from a Nurse to a Health Care Provider
S: "Hello, Dr. Smith. This is Jane, RN, from the Med Surg unit. I am calling to tell you about Ms. White in Room 210, who is experiencing increased pain and redness at her incision site. Her recent...
SBAR Report from a Nurse to a Health Care Provider
S: "Hello, Dr. Smith. This is Jane, RN, from the Med Surg unit. I am calling to tell you about Ms. White in Room 210, who is experiencing increased pain and redness at her incision site. Her recent...
4.5K


