怀孕期间慢性胰腺炎的隐患:来自大规模人口研究的证据
Chengu Niu1, Jing Zhang2, Kaiwen Zhu1
1Internal Medicine Residency Program, Rochester General Hospital, 1425 Portland Avenue, Rochester, NY 14621, USA.
概括
孕妇患慢性胰腺炎会增加妊娠糖尿病,高血压并发症,早产和胎儿死亡的风险. 这凸显了需要仔细的预设咨询和管理的需要.
科学领域:
- 产科和妇科 产科和妇科
- 胃肠病学 胃肠病学
- 公共卫生 公共卫生
背景情况:
- 慢性胰腺炎会影响生育年龄的女性,对孕产妇和产前期的影响尚不清楚.
- 关于患有慢性胰腺炎的女性怀孕相关风险的数据有限.
研究的目的:
- 为了调查由慢性胰腺炎复杂的怀孕中的孕产妇和产周结局.
- 为医疗保健提供者提供信息,以便提供更好的咨询和临床决策.
主要方法:
- 从国家住院患者样本数据库 (2009-2019) 中回顾性分析医院出院记录.
- 调查初级母亲和围产期结局.
主要成果:
- 慢性胰腺炎与妊娠糖尿病 (AOR 1.63) 和妊娠高血压并发症 (AOR 2.48) 的增加率有关.
- 患有慢性胰腺炎的孕妇出现早产的可能性更高 (AOR 3.10) 和较小的妊娠年龄 (AOR 2.40).
- 酒精诱导的慢性胰腺炎带来更高的胎儿死亡风险 (OR 17.15);慢性功能衰竭增加了妊娠高血压的风险 (OR 20.09). 还注意到了更长的住院时间和费用.
结论:
- 慢性胰腺炎显著增加母亲和胎儿不良后果的风险.
- 调查结果强调,对于患有慢性胰腺炎的女性来说,有必要进行妊娠前咨询.
- 医疗保健提供者应该意识到这些高风险,以优化患者护理.
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