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Updated: Jul 22, 2025

Modeling Chemotherapy Resistant Leukemia In Vitro
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维持治疗儿童急性淋巴细胞白血病的药理动力学模型

Anna Gebhard1, Patrick Lilienthal2, Markus Metzler3

  • 1MathOpt group, Institute of Mathematical Optimization, Faculty of Mathematics, Otto von Guericke University Magdeburg, Magdeburg, Germany. anna.gebhard@ovgu.de.

Scientific reports
|July 20, 2023
PubMed
概括

这项研究开发了儿童急性淋巴细胞白血病 (ALL) 维持药物6-mercaptopurine (6MP) 和甲状腺素 (MTX) 的药理动力学模型. 这些模型预测了个体中性粒细胞的数量,帮助个性化ALL治疗策略.

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