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Updated: Jul 22, 2025

Macrophage Differentiation and Polarization into an M2-Like Phenotype using a Human Monocyte-Like THP-1 Leukemia Cell Line
06:38

Macrophage Differentiation and Polarization into an M2-Like Phenotype using a Human Monocyte-Like THP-1 Leukemia Cell Line

Published on: August 2, 2021

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TRAF3/STAT6轴调节巨细胞两极分化和瘤进展

Jian-Hong Shi1,2,3,4, Li-Na Liu5,6, Dan-Dan Song5,6

  • 1Central Laboratory, Affiliated Hospital of Hebei University, Baoding, 071000, Hebei, China. shijianhong@hbu.edu.cn.

Cell death and differentiation
|July 20, 2023
PubMed
概括

与瘤相关的巨细胞 (TAM) 重编程是癌症治疗的关键. 由于TRAF3缺乏,它通过调节STAT6无化,抑制瘤生长和转移来促进M1巨的两极分化.

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