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手术前的乳头体积与手术前的认知障碍 (preCI) 或手术后的认知功能障碍 (POCD) 并无关联

Marinus Fislage¹, Insa Feinkohl^2,3, Friedrich Borchers⁴

¹Department of Anesthesiology and Operative Intensive Care Medicine (CCM, CVK), Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany. marinus.fislage@charite.de.

Scientific reports

|July 20, 2023

概括

这项研究发现,老年手术患者手术前的乳头体积和手术前的认知障碍或手术后的认知功能障碍之间没有显著的联系. 泰拉木斯大小没有预测手术后的认知变化.

科学领域:

神经科学是一个神经科学.
老年医学老年医学
放射学放射学是一门学科.

背景情况:

丘陵体在认知功能中起着至关重要的作用.
它对神经退行性疾病的参与越来越被认可.
对于老年手术患者来说,了解胸膜体积与认知状态的关系至关重要.

研究的目的:

研究手术前体积与手术前认知障碍 (preCI) 之间的关联.
为了确定手术前的乳头体积是否预测手术后认知功能障碍 (POCD) 在3个月.
探讨老年人选择性手术后的认知变化中丘脑的作用.

主要方法:

招募了301名65岁以上的65岁以上的患者,他们接受了没有痴呆症的选择性手术.
手术前的MRI用于通过Freesurfer.com自动分离胸部.
一个全面的神经心理测试电池评估了手术前和手术后的认知 (3个月的随访).

主要成果:

11.3%的患者有先前CI;8.3%的患者在3个月后发展为POCD.
在手术前的乳头体体积和CI前的体积之间没有发现统计学意义上的关联.
手术前的胸膜体积没有预测POCD,独立于年龄,性别和内体积.

结论:

这项研究没有证明在这个队列中,术前乳头体积与认知障碍或功能障碍之间存在显著的关联.
可能需要进一步的研究来探索体对手术患者认知变化的微妙贡献.
仅仅是thalamic体积可能不是这个人群中认知结果的可靠预测指标.

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