牙周炎与糖尿病前期的患病率和预后之间的关联:基于人口的研究
Liao Tan1,2, Jie Liu3, Zhaoya Liu4
1Department of the Geriatrics, The Third Xiangya Hospital, Central South University, Changsha, 410013, Hunan, China.
Journal of translational medicine
|July 20, 2023
概括
牙周炎与糖尿病前期的更高风险和糖尿病前期患者全因死亡率的增加有关. 管理牙周健康可能有助于预防糖尿病前期发展并降低死亡风险.
科学领域:
- 口腔健康和代谢疾病研究
- 公共卫生和流行病学.
背景情况:
- 糖尿病前期诊断和干预是预防糖尿病并发症的关键.
- 牙周炎与葡萄糖代谢失调有很强的相关性.
- 牙周状况,糖尿病前期患病率和预后之间的联系需要进一步调查.
研究的目的:
- 调查牙周炎和糖尿病前期患病率之间的关联.
- 探索牙周状况对糖尿病前期患者全因死亡率的影响.
主要方法:
- 使用了国家健康和营养检查调查 (NHANES) 数据集.
- 根据牙周炎的存在和严重程度将参与者分为不同组.
- 使用加权多变量逻辑/Cox回归模型来分析关联.
主要成果:
- 包括15,390名参与者;牙周炎组 (n=5033) 显示出更高的糖尿病前期风险.
- 更严重的牙周炎与糖尿病前期患病率正相关 (ORs 1.46-1.62).
- 在糖尿病前期患者中 (n=4518),中度和重度牙周炎与全因死亡率升高有关 (HRs 1.806-2.42).
结论:
- 牙周炎与糖尿病前期的患病率和死亡率都有积极联系.
- 有效的牙周状况管理可以作为缓解糖尿病前期发生和进展的策略.
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