缓解COVID-19相关的严重疾病的神经,认知和精神疾病的后果
Pratik Pandharipande1, Shawniqua Williams Roberson2, Fiona E Harrison3
1Department of Anesthesiology, Division of Anesthesiology Critical Care Medicine, Critical Illness, Brain Dysfunction, and Survivorship (CIBS) Center, Vanderbilt University Medical Center, Nashville, TN, USA.
长期COVID幸存者经常经历神经系统功能障碍,影响生活质量. 这篇评论探讨了长期COVID的神经,认知和精神影响,以及重症幸存者的预防策略.
科学领域:
- 神经学 神经学
- 关键护理医学 关键护理医学
- 传染性疾病 传染性疾病
背景情况:
- 数以百万计的SARS-CoV-2幸存者发展长期COVID,一种后急性感染综合征.
- 很大一部分长期COVID患者表现出神经系统功能障碍,类似于重症监护后综合征 (PICS).
- COVID-19幸存者面临长期发病的高风险,影响多个器官系统,降低生活质量和生产力.
研究的目的:
- 讨论COVID-19幸存者的神经,认知和精神疾病后果.
- 审查持续性神经心理障碍的流行病学和病理生理学.
- 概述预防策略,并强调长期COVID的研究优先事项.
主要方法:
- 审查关于长期COVID和PICS的当前知识.
- 对流行病学和病理生理学数据的分析.
- 鉴定严重疾病的基于证据的管理策略.
主要成果:
- 长期COVID经常涉及神经,认知和精神障碍.
- 神经系统功能障碍是PICS的一个常见和重叠的特征.
- 关键疾病管理影响长期的神经心理结果.
结论:
- 长期的COVID带来了重大的,持久的健康负担,带来神经心理后果.
- 在危急疾病期间,预防策略,专注于疼痛,兴奋,妄想,抗凝血和通风,至关重要.
- 对治疗方法和医疗服务考虑的进一步研究是必要的,以应对长期的COVID.
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