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Updated: Jul 22, 2025

Combined Conditional Knockdown and Adapted Sphere Formation Assay to Study a Stemness-Associated Gene of Patient-derived Gastric Cancer Stem Cells
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针对癌症中cGAS/STING信号的损失

Nobunari Sasaki1, Mizuki Homme1, Shunsuke Kitajima1

  • 1Department of Cell Biology, Cancer Institute, Japanese Foundation for Cancer Research, Tokyo, Japan.

Cancer science
|July 21, 2023
PubMed
概括

cGAS/STING通路检测细胞质DNA,从而触发免疫反应. 癌细胞抑制了这种生存途径,有助于免疫检查点阻塞的抵抗力.

关键词:
这是一种破坏DNA的毒剂.刺痛是一种刺痛.抗瘤免疫力 抗瘤免疫力cGAS 是一个气体.表观遗传抑制剂 表观遗传抑制剂

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