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在菲律宾确诊COVID-19感染的患者中使用抗菌剂:一个横截面研究

Roanne J Dominguez¹, Nicole A Domingo-Cereno¹, Rosemarie T Josue-Dominguez¹

¹Saint Louis University Hospital of the Sacred Heart, Baguio City, Philippines.

Western Pacific surveillance and response journal : WPSAR

|July 21, 2023

概括

在COVID-19患者中观察到高抗生素使用率,尽管细菌 coinfections 很少. 这凸显了在病毒爆发期间需要明智的抗生素处方来对抗抗菌素耐药性.

科学领域:

传染性疾病传染性疾病
公共卫生公共卫生
抗微生物药物管理委员会

背景情况:

由于COVID-19的流行,导致抗生素处方的增加.
过度处方抗生素有助于抗菌素耐药性.
区分病毒和细菌感染可能具有挑战性,导致实证抗生素的使用.

研究的目的:

为了确定COVID-19患者抗生素治疗的流行率.
探索抗生素处方和患者人口统计学/临床特征之间的关联.
在COVID-19大流行期间为抗生素管理实践提供信息.

主要方法:

追溯性,分析性,横截面研究.
从菲律宾的一家三级医院收集的数据 (2020年3月 - 2021年3月).
单变量和多变量逻辑回归分析.

主要成果:

在157名住院COVID-19患者中,57.3%接受了抗生素治疗.
只有1.9%的人证实了细菌共感染.
抗生素使用与双边透,COVID-19严重程度和高白细胞计数相关.

结论:

在COVID-19患者中,高抗生素使用率发生,尽管细菌共感染率低.
病毒和细菌感染之间的临床相似性可能会导致处方.
谨慎使用抗生素对于预防耐药性至关重要,与抗菌药物管理原则保持一致.

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