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部分RAG缺乏症患者的B细胞异常和自身抗体产生

Qing Min1, Krisztian Csomos2, Yaxuan Li3

  • 1Department of Clinical Immunology, Children's Hospital of Fudan University, National Children's Medical Center, Shanghai, China.

Frontiers in immunology
|July 21, 2023
PubMed
概括

部分RAG缺乏症 (pRD) 通过破坏T细胞和B细胞的耐受性,导致免疫失调. 本综述详细介绍了pRD患者的B细胞异常和自身抗体的产生.

关键词:
B细胞的耐受性巴夫 (BAFF) 是一个巴夫.CD11高高的Tbet+ B 在线观看有关 RAG 的缺陷.自抗体生产自抗体的生产.双重负B B 的一个.家庭静态的扩散扩散.

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