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撒哈拉以南非洲的恶性病和病毒感染:一篇综述

Mahamadou Diakite¹, Kathryn Shaw-Saliba², Chuen-Yen Lau³

¹University Clinical Research Center, University of Sciences, Techniques, and Technologies, Bamako, Mali.

Frontiers in virology (Lausanne, Switzerland)

|July 21, 2023

概括

病毒感染是撒哈拉以南非洲癌症的原因之一. 通过公共卫生策略预防这些感染可以显著减少该地区的癌症发病率.

科学领域:

在瘤学瘤学.
病毒学病毒学
公共卫生公共卫生

背景情况:

与病毒感染相关的恶性疾病负担在撒哈拉以南非洲 (SSA) 正在增加.
与全球平均水平相比,SSA的致癌性病毒感染患病率更高.
增加寿命和生活方式的变化有助于增加SSA的癌症负担.

研究的目的:

审查致癌病毒对撒哈拉以南非洲恶性瘤的影响.
突出SSA病毒瘤发生的区域流行病学.
讨论SSA中癌症预防的公共卫生策略.

主要方法:

关于SSA病毒致癌物和癌症的科学文献的综述.
对该地区病毒感染和相关癌症的流行病学数据的分析.
综合有关预防癌症的公共卫生干预措施的信息.

主要成果:

六种病毒 (HBV,HCV,EBV,HPV,HTLV-1,KSHV) 被确定为SSA的主要致癌物.
艾滋病毒-1通过免疫调节失调加剧瘤发生.
特定的病毒与不同的癌症有关:HBV/HCV (肝脏),HPV (宫,口,异位),EBV (淋巴瘤,鼻),KSHV (卡波西肉瘤),HTLV-1 (白血病/淋巴瘤).

结论:

像疫苗接种,更安全的做法和查等预防措施可以减少癌症病例.
解决获得医疗保健的不平等问题以及围绕癌症的禁忌至关重要.
优先考虑癌症登记册和病毒查策略对于SSA的癌症控制工作至关重要.

关键词:

撒哈拉以南非洲 (SSA)感染的感染感染.恶性瘤是一种恶性瘤.瘤发生的发生因子.病毒病毒病毒病毒

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