皮特斯托普-2及其新型衍生物RVD-127通过与小GTPases的直接相互作用来破坏全球细胞动态和核孔的完整性

Ivan Liashkovich1, Sílvio Terra Stefanello1, Reshma Vidyadharan2

  • 1Institute of Physiology II, University of Münster Münster Germany.

概括

皮特斯托普-2及其衍生物RVD-127是Ran和Rac1等小型GTPase的强有力的抑制剂,影响细胞运动和运输. 这就澄清了Pitstop-2的情况.

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