身体和心理压力对口腔微生物群的影响
Savanna Stoy1, Alexandra McMillan1, Aaron C Ericsson2
1Office of Research and Scholarly Activity, Rocky Vista University, Parker, CO, United States.
Frontiers in psychology
|July 21, 2023
概括
强化外科技能周 (ISSW) 期间的急性压力影响了军事医学学生的口腔微生物群多样性. 初步发现表明,口腔微生物组可以作为压力的有价值指标,并为压力管理策略提供信息.
科学领域:
- 微生物学 微生物学
- 人体生理学 人体生理学
- 医学教育 医学教育
背景情况:
- 口腔微生物群,一个复杂的微生物群体,在人类健康和疾病中起着至关重要的作用.
- 微生物多样性通常与更好的健康结果有关,而压力可以减少这种多样性,可能导致失生症.
- 强化外科技能周 (ISSW),为军事医学学生提供高压力模拟,为研究急性压力对口腔微生物群的影响提供了一个独特的环境.
研究的目的:
- 调查假设ISSW期间的高压模拟事件会影响军事医学学生口腔微生物组的组成和多样性.
- 探索口腔微生物组作为生理和心理压力的生物标志物的潜力.
主要方法:
- 其中包括37名参加ISSW的第二年和第三年的军事医学学生.
- 在模拟周之前和之后,从三个团队中的64名参与者收集了口腔样本.
- 进行了超基因组分析,以评估口腔微生物组合和多样性的变化.
主要成果:
- 从ISSW开始到结束时,观察到口腔微生物物种丰富度的整体增加.
- 在研究期间,14种细菌物种在丰富度上显示出显著的变化.
- 与二年级学生相比,医学三年级学生表现出更大的物种丰富性和口腔微生物组丰富性的统计学上显著差异.
结论:
- 初步数据表明,急性身体和心理压力,例如在ISSW期间经历的压力,可以改变口腔微生物组的组成和多样性.
- 口腔微生物组显示出作为压力指标的前景.
- 这些发现可能会支持通过口腔微生物组分析开发压力管理干预措施.
相关概念视频
Psychological Responses to Stress
76
Psychological responses to stress encompass the various cognitive and emotional reactions individuals experience when faced with challenging or threatening situations, such as a job loss. Prolonged exposure to stressors can disturb emotional balance, increasing negative emotions (e.g., anxiety and sadness) and diminishing positive emotions (e.g., joy and satisfaction). These persistent emotional shifts are associated with an increased risk of both physical illness and mental health issues, such...
76
Introduction to Stress and Lifestyle
145
Stress is a multifaceted response to events perceived as challenging or threatening, highlighting physical, emotional, cognitive, and behavioral reactions. Physically, stress can lead to fatigue, sleep disruptions, and various health issues such as frequent colds, chest pains, and nausea. Emotionally, it can manifest as anxiety, depression, irritability, and anger triggered by both minor and major life events. Cognitively, it may result in difficulty in concentration, memory, and...
145
Stress and Mental Health
183
Chronic stress profoundly affects mental health, significantly influencing mood, behavior, and overall quality of life. Research closely links chronic stress with mental health conditions such as depression, anxiety, and substance use disorders. Ongoing exposure to stress can lead to physiological and psychological changes, initiating a cycle of emotional distress and maladaptive coping mechanisms.
Individuals with depression often experience challenges in both their personal and professional...
Individuals with depression often experience challenges in both their personal and professional...
183
Psychoneuroimmunology: Cardiovascular Disease
54
Psychoneuroimmunology (PNI) is a multidisciplinary field that examines how psychological factors, particularly stress, interact with the immune system and impact physical health. Research in PNI has shown that chronic or traumatic stress can disrupt both the hypothalamic-pituitary-adrenal axis and the sympathetic nervous system. These disruptions contribute to serious health conditions, including cardiovascular diseases.
A key area of focus in PNI is the relationship between stress and coronary...
A key area of focus in PNI is the relationship between stress and coronary...
54
Physiological Foundation of Stress
85
Stress triggers a coordinated physiological response involving the sympathetic nervous system (SNS) and the hypothalamic-pituitary-adrenal (HPA) axis. This dual activation ensures that the body is prepared for both immediate and prolonged stress management. The process begins with the perception of a stressor. This initial phase activates the SNS, leading to the rapid release of adrenaline (epinephrine) from the adrenal glands.
Role of the Sympathetic Nervous System
Adrenaline triggers the...
Role of the Sympathetic Nervous System
Adrenaline triggers the...
85
Types of Stressors
229
A stressor is any event, condition, or stimulus that triggers stress and causes a physical or psychological response in the body. Stressors can be categorized into three main types: catastrophes; significant life changes; and daily hassles, including social stress. Each can be detrimental to physical and mental well-being.
Catastrophes
Catastrophes refer to large-scale, unpredictable events that create overwhelming stress and a sense of threat. Examples include natural disasters like...
Catastrophes
Catastrophes refer to large-scale, unpredictable events that create overwhelming stress and a sense of threat. Examples include natural disasters like...
229


