科比奥 (KOBIO) 是首个基于网络的韩国生物药物注册表,在不同疾病实体之间使用统一平台运行
Jinhyun Kim1, Jung Hee Koh2, Sung Jae Choi3
1Department of Internal Medicine, Chungnam National University College of Medicine, Daejeon, Korea.
Journal of rheumatic diseases
|July 21, 2023
概括
韩国风湿病学学院生物药物和向治疗 (KOBIO) 登记册收集了针对风湿病的生物和向合成修饰疾病的抗风湿药物 (DMARD) 的数据. 这种强大的数据库有助于研究,以提高患者治疗结果.
科学领域:
- 类风湿病学 类风湿病学
- 临床研究 临床研究
- 观察性队列研究是观察性队列研究.
背景情况:
- 韩国风湿病学学院生物药物和向治疗 (KOBIO) 注册表于2012年12月建立.
- 这是一项全国性的观察性队列研究.
- 该注册中心专注于患有类风湿性关节炎,结性脊柱炎和牛皮性关节炎的患者.
研究的目的:
- 为了前性地研究临床表现和结果.
- 获取生物和向合成疾病修饰性抗风湿药物 (DMARD) 暴露的详细数据.
- 为了比较患者在传统的DMARDs与先进疗法的患者的结果.
主要方法:
- 关于人口统计,疾病活动,治疗和不良事件的前性数据收集.
- 使用基于网络的统一平台进行年度跟进.
- 包括开始或切换生物或向合成DMARDs的患者.
主要成果:
- 超过5500名患者从韩国各地的47个中心注册.
- 收集各种类风湿病的综合数据.
- 作为临床研究的强大数据库.
结论:
- 科比奥注册表是改善治疗质量的宝贵资源.
- 它促进了旨在提高类风湿性疾病临床结果的研究.
- 该注册表支持基于证据的风湿病学实践.
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