中国中老年人和老年人中消化系统疾病和肉症之间的关联:基于全国代表性调查的前性队列研究
Guanghui Cui1,2, Shaojie Li3,4, Hui Ye1,2
1Department of Integrated Traditional Chinese and Western Medicine, Peking University First Hospital, Beijing, China.
Frontiers in nutrition
|July 21, 2023
概括
在45岁以上的成年人中,消化系统疾病增加了与年龄相关的肌肉损失 (sarcopenia) 的风险. 早期治疗消化系统疾病可能有助于预防肉症的发生.
科学领域:
- 老年学是指老年学的学科.
- 胃肠病学 胃肠病学
- 公共卫生 公共卫生
背景情况:
- 消化系统疾病很常见,可能导致营养不良,可能导致肌肉损失.
- 老年人消化系统疾病和肉症 (与年龄相关的肌肉损失) 之间的联系仍然不清楚.
研究的目的:
- 为了研究消化系统疾病与患上皮病的风险之间的纵向关联.
- 通过国家健康调查,分析中老年和老年中国成年人的这种关联.
主要方法:
- 来自中国健康与退休长度研究 (CHARLS) 的7,025名年龄≥45岁的成年人的前性队列研究.
- 通过自我报告识别的消化系统疾病;使用2019年亚洲肉病工作组标准 (肌肉力量,性能,质量) 评估的肉病.
- 考克斯危险回归分析对15个共变量进行了调整.
主要成果:
- 消化系统疾病的患病率为22.6%,肉症的发病率为8.5%.
- 经过对共变量进行调整后,消化系统疾病与缩症的风险增加显著相关 (HR=1.241,P<0.05).
- 这种关联在男性,老年人 (60-79岁),农村居民和已婚个人中更为强烈.
结论:
- 消化系统疾病与45岁及以上的成年人中肉类的发病率较高有关.
- 对于消化系统疾病的早期干预可能是缓解这种人群中萨科佩尼亚发展的策略.
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