一个回顾性数据库研究,研究了第一发精神病的2年体重轨迹
Yi Chian Chua1, Edimansyah Abdin2, Charmaine Tang1
1Department of Psychosis, Institute of Mental Health, Singapore, Singapore.
Frontiers in psychiatry
|July 21, 2023
概括
这项研究在早期精神病患者中确定了明显的两年体重轨迹. 很大一部分 (38.6%) 属于超高风险组,这凸显了需要进行体重管理干预的必要性.
科学领域:
- 精神病学和心理健康 精神病学和心理健康
- 临床研究 临床研究
- 公共卫生 公共卫生
背景情况:
- 个体体重概况对于在异质临床群体中量身定制治疗至关重要.
- 早期精神病干预计划 (EPIP) 提供了一个独特的环境来研究体重变化.
研究的目的:
- 确定和描述新加坡早期精神病干预计划 (EPIP) 中患者的两年体重轨迹.
- 根据两年时间内的体重变化风险对患者进行分类.
主要方法:
- 对391名接受EPIP (2014-2018) 的精神分裂谱系障碍患者的非识别数据的回顾性分析.
- 在基线,1年和2年随访期间收集人体统计,社会人口统计和临床数据.
- 利用权重变化数据来定义风险类别.
主要成果:
- 分析了391个完整的数据集.
- 缺少体重数据的患者更有可能是年长,男性,受过高等教育,并且不接受治疗的精神病持续时间更长.
- 体重轨迹将患者分为风险组:38.6%超高风险,34.0%高风险减轻,4.3%风险,8.8%延迟风险和14.4%低风险.
结论:
- 早期精神病患者的体重轨迹可以分为不同的风险组.
- 超高和高风险类别的高比例患者强调了有针对性的体重管理的必要性.
- 未来的研究应该纳入药理学,饮食和体育活动数据,以便早期检测和干预.
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