慢性胰腺炎中骨质病的患病率:系统性审查和元分析
Daryl Ramai1, Antonio Facciorusso2, Marcello Maida3
1Division of Gastroenterology, Hepatology, and Nutrition, University of Utah Health, Salt Lake City, Utah, USA.
Clinical and translational gastroenterology
|July 21, 2023
概括
慢性胰腺炎 (CP) 患者患有骨质疏松症,骨质疏松症和骨质疏松症的患病率很高. 风险因素包括吸烟,饮酒和维生素水平低,这突显了对CP患者骨健康监测的必要性.
科学领域:
- 胃肠病学和肝病学
- 内分泌学和新陈代谢学
- 骨健康研究 骨健康研究
背景情况:
- 慢性胰腺炎 (CP) 显著增加营养缺乏和并发症的风险.
- 骨健康是慢性胰腺炎患者护理的一个关键,经常被忽视的方面.
研究的目的:
- 在慢性胰腺炎患者中提供骨质病,骨质疏松症和骨质疏松症的最新流行率估计.
- 在这个人群中确定与骨矿物质密度下降相关的关键预测因素.
主要方法:
- 进行了发表文献的系统审查和元分析.
- 搜索策略包括从创建到2021年10月的主要数据库.
- 双能X射线吸收计 (DXA) 扫描数据和风险因素使用随机效应模型进行了分析.
主要成果:
- 骨质疏松症的综合患病率为58%,骨质疏松症为18%,骨质疏松症为39%.
- 导致骨矿物质密度下降的重要危险因素包括吸烟,饮酒,年龄较大,女性性别,低BMI和维生素D和K缺乏.
结论:
- 患有慢性胰腺炎的患者表现出高水平的骨质病变,需要积极评估骨健康状况.
- 需要进一步的纵向研究来阐明CP的疾病进展和骨损失模式.
相关概念视频
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